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If you are interested in learning more about or participating in BRIDGE, please visit the BRIDGE Clinical Sites map for a list of sites currently participating in BRIDGE. to see the BRIDGE Study posting on Clinical

For more information about participating in clinical trials, please visit the Center for Information & Study on Clinical Research Participation

Why Participate?

Overall, there is uncertainty about the benefit or harm of bridging anticoagulation. This research study will determine the possible benefits and harms of bridging anticoagulation and will inform doctors about the best way to care for patients like you in the future.

Some doctors switch patients from warfarin to heparin around the time of surgeries and procedures (“bridging anticoagulation”), while others simply stop the warfarin. There has never been a controlled study to determine which of these strategies is the best one to prevent arterial thrombotic events (ATEs) or clotting.

Who Should Be Involved?

Adults with atrial fibrillation or flutter who are taking coumadin (warfarin) and are scheduled to have a surgery or procedure.

Select More to see if you might be eligible for the study.

Frequently Asked Questions

What is atrial fibrillation or atrial flutter?

What is warfarin?

Why do patients receive warfarin therapy for atrial fibrillation or atrial flutter?

What is the usual care for people who are receiving warfarin therapy and need surgery or a procedure?

What is the purpose of the BRIDGE study?

Why is this research study being done?

What will happen if I agree to participate in this research study?

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« March 2015 »